FWE.12.5
02.Aug.2024
02.Aug.2025
SUGGESTED USE
Adults take 2 capsules daily post breakfast, with a glass of water or as suggested by your Healthcare Professional.
Product Information
Unived’s Eye Health is formulated with natural carotenoids Lutein and Zeaxanthin both derived from the Marigold flower and beta-carotene from Blakeslea trispora, Grape seed extract, Vitamin C, D, E, folate, and Zinc to promote optimal eye health, support eye function, and help strengthen the immune system of the eye.
Carotenoids are made by plants and are found in various green leafy vegetables. In the body, Lutein and Zeaxanthin are found in the retina and lens where they act as natural antioxidants and help absorb damaging high-energy blue light and ultraviolet light. Beta-carotene is used to make vitamin A, which is required by the retina to detect light and convert it into electrical signals. Proanthocyanidins from Grape seed extract offers ocular health promotion. Other key vitamins and minerals ensure to prevent possible deficiencies and help to strengthen the immune system of the eye.
Unived’s Eye Health is ideal for people who are exposed to long-term digital eye strain, for people with reduced visual acuity, for people with age-related eye disorders, and for people looking to protect their eyes from oxidative stress and improve overall eyesight.
Key Benefits
- Filters blue light due to excessive screen time.
- Reduces eye strain.
- Promotes better sleep, focus, and eyesight.
- Supports macular pigment for long-term eye health.
- Reduces symptoms associated with digital eye strain such as fatigue, headaches, and blurred vision.
Ingredients
- Grape Seed Extract (Vitis vinifera Seed Extract Standardized to 95% Proanthocyanidis) - 147mg
- Ascorbic Acid – 80mg
- Zinc Citrate – 57mg
- Lutein with Zeaxanthin – 50mg
- Natural Beta-Carotene from Blakeslea trispora – 30mg
- Naturall-e™ as d-Alpha-Tocopherol from Soya Oilseeds – 30mg
- Vitashine™ as Chalecalciferol from Linchen – 6mg
- L-5 Methylterahydrofolate (95%) – 316mcg
- Methylcobalamin (98%) – 2.24mcg
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Globally, approximately 250 million people suffer from varying degrees of vision loss. Leading causes include several eye conditions such as cataracts, age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy. These conditions disproportionately affect older adults, and with an aging population, the number of affected individuals is predicted to increase exponentially [1].
Whilst the aetiology-related eye disease is complex and multifactorial, oxidative stress has been implicated as a common causative mechanism. The eye is particularly susceptible to oxidative stress as a result of its high oxygen consumption, high concentration of polyunsaturated fatty acids, and cumulative exposure to high-energy visible light. This combination of factors leads to the generation of reactive oxygen species that can trigger oxidative damage to ocular tissues [1].
Consequently, there has been significant research interest in the role of dietary antioxidants and the potential therapeutic benefits of antioxidant, vitamin, and mineral supplements as a simple and cost-effective strategy for disease prevention and/or control [1].
References:
1. Lawrenson, John G., and Laura E. Downie. "Nutrition and eye health." Nutrients 11.9 (2019): 2123.
Whilst the aetiology-related eye disease is complex and multifactorial, oxidative stress has been implicated as a common causative mechanism. The eye is particularly susceptible to oxidative stress as a result of its high oxygen consumption, high concentration of polyunsaturated fatty acids, and cumulative exposure to high-energy visible light. This combination of factors leads to the generation of reactive oxygen species that can trigger oxidative damage to ocular tissues [1].
Consequently, there has been significant research interest in the role of dietary antioxidants and the potential therapeutic benefits of antioxidant, vitamin, and mineral supplements as a simple and cost-effective strategy for disease prevention and/or control [1].
References:
1. Lawrenson, John G., and Laura E. Downie. "Nutrition and eye health." Nutrients 11.9 (2019): 2123.
Unived’s Eye Health contains a combination of carotenoids, proanthocyanidins, vitamins, and minerals that exert a versatile mode of action in promoting overall eye health.
Mode of Action:
1. Lutein and Zeaxanthin are two principal components that build the macular pigment of the retina [2]. Has antioxidant properties and protects retinal pigment from phototoxic light damage by acting as a filter for harmful light rays [4]. Improves macular pigment optical density, thereby reducing the risk of age-related macular degeneration (AMD) [5].
2. Grape seed extract protects eye cells from oxidative stress [11]. Studies show that phytochemicals from grapes, like proanthocyanidins, can help minimize various eye issues. This includes macular degeneration, uvea issues, cataracts, red eye, diabetic retinopathy, retinal thickening, and eye cell damage [12] [13]. Research indicates proanthocyanidins are involved in reducing these eye defects [11].
3. Beta-carotene: A precursor to Vitamin A, plays a major role in the pathways that are responsible for generating vision. May reduce the risk of developing advanced AMD. Supports the function of the cornea, which is the protective layer of the eye, and helps keep the eye lubricated, preventing dry eyes [5] [6].
4. Zinc: This plays an important role in the metabolism of the retina and the lens of the eye. Zinc is considered to have an interaction with vitamin A in the generation of the visual pigments of the retina; night blindness occurs with zinc deficiency even in the presence of adequate vitamin A [6].
5. Vitamin C: Acts as a powerful antioxidant and regenerates Vitamin E. Protects the retina against light damage. Shown to reduce the risk of UV-induced cataracts [6].
6. Vitamin E: Benefits to ocular health include effects on the expression and activities of molecules and enzymes in immune and inflammatory cells [9]. Prevent oxidative damage and plays an important role in maintaining a strong immune system in the eye [6].
7. Vitamin D: Studies demonstrate that vitamin D significantly reduces signs of retinal inflammation [10].
8. Folate: Folate or Vitamin B9 plays a vital role in the pathways that involve the breakdown of homocysteine levels thus preventing its implications on eye health [11].
References:
2. Ribaya-Mercado, Judy D., and Jeffrey B. Blumberg. "Lutein and zeaxanthin and their potential roles in disease prevention." Journal of the American College of Nutrition 23.sup6 (2004): 567S-587S.
3. Stahl, W. "Macular carotenoids: lutein and zeaxanthin." Nutrition and the Eye 38 (2005): 70-88.
4. Arunkumar, Ranganathan, Aruna Gorusupudi, and Paul S. Bernstein. "The macular carotenoids: A biochemical overview." Biochimica et biophysica acta (BBA)-Molecular and cell biology of lipids 1865.11 (2020): 158617.
5. Manzi, Fiona, et al. "The intake of carotenoids in an older Australian population: The Blue Mountains Eye Study." Public Health Nutrition 5.2 (2002): 347-352.
6. Brown, Nicholas A. Phelps, et al. "Nutrition supplements and the eye." Eye 12.1 (1998): 127-133.
7. Rasmussen HM, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 2013;8:741-8. doi: 10.2147/CIA.S45399. Epub 2013 Jun 19. PMID: 23818772; PMCID: PMC3693724.
8. Lee V, Rekhi E, Hoh Kam J, Jeffery G. Vitamin D rejuvenates aging eyes by reducing inflammation, clearing amyloid beta and improving visual function. Neurobiol. Aging. 2012;33:2382–2389.
9. Tan, Ava Grace, et al. "Serum homocysteine, vitamin B12, and folate, and the prevalence and incidence of posterior subcapsular cataract." Investigative ophthalmology & visual science 56.1 (2015): 216-220.
10. Natarajan, Sithranga Boopathy, et al. "Ocular promoting activity of grape polyphenols—A review." Environmental toxicology and pharmacology 50 (2017): 83-90.
11. Jia, Zhiyan, et al. "Grape seed proanthocyanidin extract protects human lens epithelial cells from oxidative stress via reducing NF-кB and MAPK protein expression." Molecular vision 17 (2011): 210.
12. Sochorova, Lenka, et al. "Health effects of grape seed and skin extracts and their influence on biochemical markers." Molecules 25.22 (2020): 5311.
13. Moon, Sang Woong, et al. "Effect of grape seed proanthocyanidin extract on hard exudates in patients with non-proliferative diabetic retinopathy." Medicine 98.21 (2019): e15515.
Mode of Action:
1. Lutein and Zeaxanthin are two principal components that build the macular pigment of the retina [2]. Has antioxidant properties and protects retinal pigment from phototoxic light damage by acting as a filter for harmful light rays [4]. Improves macular pigment optical density, thereby reducing the risk of age-related macular degeneration (AMD) [5].
2. Grape seed extract protects eye cells from oxidative stress [11]. Studies show that phytochemicals from grapes, like proanthocyanidins, can help minimize various eye issues. This includes macular degeneration, uvea issues, cataracts, red eye, diabetic retinopathy, retinal thickening, and eye cell damage [12] [13]. Research indicates proanthocyanidins are involved in reducing these eye defects [11].
3. Beta-carotene: A precursor to Vitamin A, plays a major role in the pathways that are responsible for generating vision. May reduce the risk of developing advanced AMD. Supports the function of the cornea, which is the protective layer of the eye, and helps keep the eye lubricated, preventing dry eyes [5] [6].
4. Zinc: This plays an important role in the metabolism of the retina and the lens of the eye. Zinc is considered to have an interaction with vitamin A in the generation of the visual pigments of the retina; night blindness occurs with zinc deficiency even in the presence of adequate vitamin A [6].
5. Vitamin C: Acts as a powerful antioxidant and regenerates Vitamin E. Protects the retina against light damage. Shown to reduce the risk of UV-induced cataracts [6].
6. Vitamin E: Benefits to ocular health include effects on the expression and activities of molecules and enzymes in immune and inflammatory cells [9]. Prevent oxidative damage and plays an important role in maintaining a strong immune system in the eye [6].
7. Vitamin D: Studies demonstrate that vitamin D significantly reduces signs of retinal inflammation [10].
8. Folate: Folate or Vitamin B9 plays a vital role in the pathways that involve the breakdown of homocysteine levels thus preventing its implications on eye health [11].
References:
2. Ribaya-Mercado, Judy D., and Jeffrey B. Blumberg. "Lutein and zeaxanthin and their potential roles in disease prevention." Journal of the American College of Nutrition 23.sup6 (2004): 567S-587S.
3. Stahl, W. "Macular carotenoids: lutein and zeaxanthin." Nutrition and the Eye 38 (2005): 70-88.
4. Arunkumar, Ranganathan, Aruna Gorusupudi, and Paul S. Bernstein. "The macular carotenoids: A biochemical overview." Biochimica et biophysica acta (BBA)-Molecular and cell biology of lipids 1865.11 (2020): 158617.
5. Manzi, Fiona, et al. "The intake of carotenoids in an older Australian population: The Blue Mountains Eye Study." Public Health Nutrition 5.2 (2002): 347-352.
6. Brown, Nicholas A. Phelps, et al. "Nutrition supplements and the eye." Eye 12.1 (1998): 127-133.
7. Rasmussen HM, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 2013;8:741-8. doi: 10.2147/CIA.S45399. Epub 2013 Jun 19. PMID: 23818772; PMCID: PMC3693724.
8. Lee V, Rekhi E, Hoh Kam J, Jeffery G. Vitamin D rejuvenates aging eyes by reducing inflammation, clearing amyloid beta and improving visual function. Neurobiol. Aging. 2012;33:2382–2389.
9. Tan, Ava Grace, et al. "Serum homocysteine, vitamin B12, and folate, and the prevalence and incidence of posterior subcapsular cataract." Investigative ophthalmology & visual science 56.1 (2015): 216-220.
10. Natarajan, Sithranga Boopathy, et al. "Ocular promoting activity of grape polyphenols—A review." Environmental toxicology and pharmacology 50 (2017): 83-90.
11. Jia, Zhiyan, et al. "Grape seed proanthocyanidin extract protects human lens epithelial cells from oxidative stress via reducing NF-кB and MAPK protein expression." Molecular vision 17 (2011): 210.
12. Sochorova, Lenka, et al. "Health effects of grape seed and skin extracts and their influence on biochemical markers." Molecules 25.22 (2020): 5311.
13. Moon, Sang Woong, et al. "Effect of grape seed proanthocyanidin extract on hard exudates in patients with non-proliferative diabetic retinopathy." Medicine 98.21 (2019): e15515.
What is the suggested use of Unived’s Eye Health Formula?
Adults take 2 capsules per day post breakfast with a glass of water or as suggested by your Healthcare Professional.
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FWE.12.5
02.Aug.2024
02.Aug.2025
SUGGESTED USE
Adults take 2 capsules daily post breakfast, with a glass of water or as suggested by your Healthcare Professional.