SUGGESTED USE
Adults take 1 capsule daily post meal, with a glass of water.
Product Information
Unived’s resveratrol contains 500mg of Trans-Resveratrol, an active form of resveratrol. It has antioxidant, anti-inflammatory, cardiovascular protection, antidiabetic, neuroprotection, and antiaging effects. Resveratrol is now looked at as an effective compound for supporting healthy aging and managing age-related diseases (1).
Key Benefits
- Supports healthy aging & longevity
- Supports the antioxidant system and helps to reduce inflammation
- Supports cardiovascular & brain health
- Supports cellular health
Ingredient Information
- Trans-Resveratrol (95%) – 527mg
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What is Resveratrol?
Resveratrol is a natural compound that belongs to a class of plant chemicals called polyphenols. It is found in a variety of plants, including grapes (especially red grapes), berries, peanuts, and certain herbs like Japanese knotweed (3).
Resveratrol gained attention due to its presence in red wine and its potential health benefits. It is known for its antioxidant properties, meaning it helps protect cells from damage caused by harmful free radicals. It is also recognized for its anti-inflammatory effects (4).
Resveratrol is an activator of SIRT1, a sirtuin family of proteins, and therefore hypothesized to be beneficial in diseases associated with abnormal metabolic control, inflammation, and cell cycle defects (5). Therefore it is now been looked at as a healthy aging compound.
Benefits:
1. Antioxidant and anti-inflammatory effects: Resveratrol acts as an antioxidant, helping to protect cells from damage caused by free radicals. It also has anti-inflammatory properties, which may help reduce inflammation in the body (6).
2. Cardiovascular health: Resveratrol has been studied for its potential cardiovascular benefits. It may help improve blood flow, reduce LDL (bad) cholesterol levels, and reduce the formation of blood clots, thereby reducing the risk of heart disease (7).
3. Brain health: Some studies suggest that resveratrol may have neuroprotective properties and could potentially benefit brain health. It has been linked to improvements in memory and cognitive function and may help protect against age-related cognitive decline and neurodegenerative diseases such as Alzheimer's disease (8).
4. Anti-cancer properties: In laboratory studies, Resveratrol has been shown to have anti-cancer effects. It may help inhibit cancer cell growth, prevent tumor formation, and induce apoptosis (cell death) in cancer cells. However, more research is needed to determine its efficacy in human cancer treatment (9).
5. Longevity: Resveratrol has been associated with increased lifespan in certain animal studies. It activates a protein called SIRT1, which is involved in regulating cellular processes associated with aging. However, the impact of resveratrol on the human lifespan is still unclear and requires further investigation (10).
References:
1. Effects and Mechanisms of Resveratrol on Aging and AgeRelated Diseases Dan-Dan Zhou , 1 Min Luo , 1 Si-Yu Huang , 1 Adila Saimaiti , 1 Ao Shang , 1 Ren-You Gan , 2,3 and Hua-Bin Li 1
2. Zhou, D. D., Luo, M., Huang, S. Y., Saimaiti, A., Shang, A., Gan, R. Y., & Li, H. B. (2021). Effects and Mechanisms of Resveratrol on Aging and Age-Related Diseases. Oxidative medicine and cellular longevity, 2021, 9932218.
3. Ramírez-Garza, S. L., Laveriano-Santos, E. P., Marhuenda-Muñoz, M., Storniolo, C. E., Tresserra-Rimbau, A., Vallverdú-Queralt, A., & Lamuela-Raventós, R. M. (2018). Health Effects of Resveratrol: Results from Human Intervention Trials. Nutrients, 10(12), 1892.
4. Khattar, S., Khan, S. A., Zaidi, S. A. A., Darvishikolour, M., Farooq, U., Naseef, P. P., Kurunian, M. S., et al. (2022). Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential. Pharmaceuticals, 15(8), 957. MDPI AG.
5. Berman, A. Y., Motechin, R. A., Wiesenfeld, M. Y., & Holz, M. K. (2017). The therapeutic potential of resveratrol: a review of clinical trials. NPJ precision oncology, 1, 35.
6. Meng, T., Xiao, D., Muhammed, A., Deng, J., Chen, L., & He, J. (2021). Anti-Inflammatory Action and Mechanisms of Resveratrol. Molecules (Basel, Switzerland), 26(1), 229.
7. Gligorijević, N., Stanić-Vučinić, D., Radomirović, M., Stojadinović, M., Khulal, U., Nedić, O., & Ćirković Veličković, T. (2021). Role of Resveratrol in Prevention and Control of Cardiovascular Disorders and Cardiovascular Complications Related to COVID-19 Disease: Mode of Action and Approaches Explored to Increase Its Bioavailability. Molecules (Basel, Switzerland), 26(10), 2834.
8. Cicero, A. F. G., Ruscica, M., & Banach, M. (2019). Resveratrol and cognitive decline: a clinician perspective. Archives of medical science : AMS, 15(4), 936–943.
9. Ko, J. H., Sethi, G., Um, J. Y., Shanmugam, M. K., Arfuso, F., Kumar, A. P., Bishayee, A., & Ahn, K. S. (2017). The Role of Resveratrol in Cancer Therapy. International journal of molecular sciences, 18(12), 2589.
10. Pyo, I. S., Yun, S., Yoon, Y. E., Choi, J. W., & Lee, S. J. (2020). Mechanisms of Aging and the Preventive Effects of Resveratrol on Age-Related Diseases. Molecules (Basel, Switzerland), 25(20), 4649.
Research on resveratrol has explored its potential benefits for various health conditions, including cardiovascular diseases, neurodegenerative disorders, cancer, and metabolic conditions like obesity and diabetes. However, it's important to note that while some studies have shown promising results, the overall effects of resveratrol on human health are still being investigated, and more research is needed to fully understand its potential benefits and optimal dosage (1, 2).
References:
1. Berman, A. Y., Motechin, R. A., Wiesenfeld, M. Y., & Holz, M. K. (2017). The therapeutic potential of resveratrol: a review of clinical trials. NPJ precision oncology, 1, 35.
2. Khattar, S., Khan, S. A., Zaidi, S. A. A., Darvishikolour, M., Farooq, U., Naseef, P. P., Kurunian, M. S., et al. (2022). Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential. Pharmaceuticals, 15(8), 957. MDPI AG.
What is resveratrol?
Resveratrol is a natural compound found in certain plants, particularly in the skin of red grapes. It is classified as a polyphenol and is known for its antioxidant properties. 1.
What are the potential benefits of resveratrol supplementation?
Resveratrol supplementation has been associated with potential benefits such as cardiovascular health, brain function, anti-inflammatory effects, and potential anti-cancer properties. However, more research is needed to fully understand its effects.
Is resveratrol safe to take as a supplement?
Resveratrol is generally considered safe for most people when taken at appropriate dosages. However, it may interact with certain medications or have adverse effects in specific individuals. It's important to consult with a healthcare professional before starting any new supplement regimen.
What is the recommended dosage of resveratrol?
There is no established recommended daily dosage for resveratrol. Supplement dosages typically range from 250 mg to 500 mg per day, but individual needs may vary. It's advisable to follow the instructions on the specific product and consult with a healthcare professional for personalized advice.
Can resveratrol supplements replace a healthy diet?
Resveratrol supplements should not be seen as a replacement for a healthy diet. It is best to obtain nutrients, including resveratrol, from a well-rounded diet that includes a variety of fruits, vegetables, and other whole foods.
Can resveratrol supplements interact with medications? •
Resveratrol supplements may interact with certain medications, including blood thinners and medications metabolized by the liver. It's important to discuss with a healthcare professional if you are taking any medications to determine if resveratrol supplementation is suitable for you.
Are there any side effects of resveratrol supplementation? •
Resveratrol is generally well-tolerated, but some individuals may experience gastrointestinal symptoms such as nausea or diarrhea. If you experience any adverse effects, it's advisable to discontinue use and consult with a healthcare professional.
Can everyone benefit from resveratrol supplementation?
Resveratrol supplementation may be beneficial for certain individuals, but its effects can vary. It's best to consult with a healthcare professional to determine if resveratrol supplementation is appropriate for your specific health needs and goals.
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SUGGESTED USE
Adults take 1 capsule daily post meal, with a glass of water.