SUGGESTED USE
Adults take 1 capsule daily post dinner or 20 minutes before bedtime, with a glass of water.
Product Information
Vaginal FLORA is formulated specifically for women's health and wellness. It contains 10 billion colony-forming units of a clinically documented probiotic blend with L. rhamnosus HN001 and L. acidophilus to support a healthy vaginal microbiome. It helps normalize vaginal pH, rebalance vaginal bacteria to prevent yeast overgrowth, and restore bacterial balance during vaginal dysbiosis. This product is well-suited for women seeking to maintain vaginal health, especially those prone to vaginal infections and bacterial vaginosis.
Key Benefits
- Helps maintain healthy vaginal pH at 3.5-4.5
- Promotes a balanced vaginal microbiota
- Supports restoration of vaginal health
- Helps prevent yeast overgrowth.
- Supports and normalizes vaginal health during vaginal dysbiosis.
- Supports bacterial and yeast balance.
- Supports overall vaginal health/wellness.
Ingredient Information
- HOWARU® Feminine (10 Billion CFU) Containing Lactobacillus rhamnosus (HN001™) + Lactobacillus acidophilus (La-14™) – 143mg
- Other Ingredient HPMC Vegetarian Capsule
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The vaginal microbiome is a complex microenvironment that undergoes dynamic fluctuations throughout a woman's menstrual cycle and lifetime. Vaginal infections are among the most common gynecological issues faced by women [3]. Common vaginal infections include bacterial vaginosis, vaginal candidiasis, etc [4].
Bacterial vaginosis (BV) is the most prevalent vaginal infection globally, caused by an imbalance in the vaginal microbiota among women of reproductive age. BV occurs when harmful bacteria overgrow, disrupting the natural bacterial balance in the vagina [1].
The vaginal microbiome houses a diverse array of microorganisms. A healthy vagina is identified by the presence of Lactobacilli. These bacilli produce lactic acid, biosurfactants, bacteriocin-like compounds, and hydrogen peroxide, which acidify the vaginal environment creating a pH between 3.5-4.5, allowing Lactobacilli to compete for nutrients and inhibit pathogenic microbial adhesion and proliferation on vaginal surfaces. Together, this promotes a balanced vaginal microbiome [2].
An imbalance with reduced Lactobacilli is associated with various infections that can lead to vaginal dysbiosis. Dysbiosis relates to conditions like bacterial vaginosis, vulvovaginal candidiasis, aerobic vaginitis, and sexually transmitted infections. Serious health issues have been linked to these infections, such as infertility, preterm birth, pelvic inflammatory disease, premature membrane rupture, and miscarriage [2].
Maintaining a balanced vaginal microbiota is important for women's health, as it reduces risks of infection, gynecological complications, successful fertilization, and healthy pregnancy outcomes.
References:
1. Kairys, Norah, Karen Carlson, and Manish Garg. "Gardnerella Vaginalis." (2017).
2. Chen, X., et al. "The female vaginal microbiome in health and bacterial vaginosis. Front. Cell Infect Microbiol 2021; 11: 631972." (2021).
3. Chen, Xiaodi, et al. "The female vaginal microbiome in health and bacterial vaginosis." Frontiers in cellular and infection microbiology 11 (2021): 631972.
4. Tempera, G. "Vaginal infections: Epidemiology and risk factors." Giornale Italiano di ostetricia e ginecologia 27.7/8 (2005): 280.
HOWARU® Feminine containing 10Billion CFU of L. rhamnosus HN001™ + L. acidophilus (La-14™)
These strains are resistant to the acidic environment of the GI tract. Research shows that when consumed orally, the strains HOWARU® L. rhamnosus HN001™ + L. acidophilus (La-14™) can migrate to the vaginal tract and balance vaginal microbiota.
In a randomized, double-blind, placebo-controlled clinical trial , a group of healthy women consumed two HOWARU® Feminine capsules once daily for 14 days. At the end of the study, women experienced a rise in vaginal Lactobacillus acidophilus and Lacticaseibacillus rhamnosus levels, which continued to increase for at least one week when compared to the placebo group.
In another clinical trial, 40 women with signs of vaginosis, reported an increase in healthy vaginal bacteria after consuming HOWARU® Feminine consistently for 15 days indicating probiotics’ benefits for balancing vaginal microbiota. The women in the probiotic group also experienced a decrease in self-assessed vaginal symptoms like itching or discharge.
The clinical trial results reveal HOWARU® Feminine targeted ability to support healthy vaginal microbiota and address symptoms of recurring vaginal infections, such as bacterial vaginosis and vulvovaginal candidiasis, when used with antibiotic or anti-fungal therapy.
Mode of action:
- The probiotic strains are able to survive passage through the gastrointestinal acids due to their resistance to both acid and bile. This allows the strains to enter the vaginal tract, where they subsequently colonize. The probiotic strains then stimulate immune function in both the gastrointestinal and vaginal tracts. Additionally, the strains produce lactic acid, hydrogen peroxide, and bacteriocin, which helps re-establish and normalize the healthy microbiota present in the vaginal environment.
What is Vaginal FLORA?
Vaginal FLORA is a probiotic supplement containing a specific blend of probiotic strains designed to support women's vaginal health.
Is it safe for pregnant/breastfeeding women?
The product is suitable for preganancy and breastfeeding. However we strongly recommend that pregnant or nursing women should always consult their healthcare provider before starting any new supplement, including Unived Women’s Probiotics.
How does Vaginal FLORA work?
It works by promoting a healthy balance of beneficial bacteria in the vagina, which can help prevent infections and maintain overall feminine health.
Who can benefit from taking Vaginal FLORA?
Women who experience recurrent vaginal infections like bacterial vaginosis, or those looking to support their overall feminine health can benefit from taking Unived Women’s Probiotics.
When is the best time to take Vaginal FLORA¬¬?
It is recommended to take one capsule after dinner or 20 minutes before bedtime with a glass of water.
Are there any side effects?
There are no side effects. But some individuals may experience mild digestive discomfort when starting probiotics which will resolve with continuous use.
How long until results are seen?
Results vary per individual, but some may start noticing improvements in feminine health within a few weeks of regular use.
Does it resolve infection symptoms?
The product works by balancing bacterial levels and restoring a healthy vaginal microbiome. When this occurs, symptoms associated with bacterial vaginosis and other possible vaginal infections will resolve.
Can it be taken with other medications?
It is recommended to consult a healthcare provider before combining any supplements with medications to avoid potential interactions.
Can it be taken with antibiotics prescribed for the bacterial vaginosis?
Yes. The product can be taken as an adjuvant to the prescribed antibiotics for bacterial vaginosis?
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SUGGESTED USE
Adults take 1 capsule daily post dinner or 20 minutes before bedtime, with a glass of water.